ONCOLOGY

At thromboDx BV we develop blood platelet-powered molecular cancer diagnostics tests. These non-invasive tests enable longitudinal monitoring of the mutational status of the tumor in blood. The changing mutational tumor profile can be monitored in blood platelets allowing for personalized tumor therapy.

 

Initially we focus on cancer indications in which there are established biomarkers and a high unmet medical need for non-invasive diagnostic tools for therapy selection and monitoring. We develop proprietary companion diagnostics that aid clinicians with therapy selection.

 

We are actively standardizing, evaluating, and validating two thromboDx product lines. We have designed amplicon Seq and PCR based assays for platelet-powered diagnostics of several biomarkers, including EGFR, KRAS, and ALK.

 

Product Line #1: Biomarker-specific amplicon Seq kits

  • barcoded amplicon adapter plasmids
  • biomarker-specific primer sets
  • enzymes and reagents

 

Product Line #2: biomarker-specific platelet PCR kits

  • biomarker-specific primer sets
  • enzymes and reagents

 

We are actively seeking partners for the co-development of platelet-powered cancer diagnostics.